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De novo NAD+ synthesis enhances mitochondrial function and improves health

Although the availability of arachidonic acid has been actively investigated as a major metabolic factor controlling PG production, it is clear that other cellular cofactors may also regulate PG biosynthesis

Recent studies on a rat model have shown that a high-fat diet significantly increases TSH levels and causes thyroid dysfunction, suggesting that excessive consumption of animal fat induces thyroid dysfunction and may contribute to the pathogenesis of hypothyroidism [145,146]

Marty et al., 2009