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A comparative efficacy trial (ARBITER6) also showed a significant reduction of baseline CIMT with extended-release nicotinic acid (2 g/day for 14 months), as opposed to ezetimibe (a cholesterol-lowering drug), in patients taking statins (84)

Biomaterials 286 , 121582 (2022)

The highest levels of COX-2 are found mainly in suprabasal keratinocytes [103, 107]

It should be noted that there are many downstream benefits to combining GSH with other ingredients like ascorbic acid and tocopherol (Vit C and Vit E) for additional and synergistic benefits like collagen production and skin lightening and antioxidant recycling respectively