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In mammals, PRDX14 preferentially detoxify H 2 O 2 , whereas PRDX5 shows higher reactivity toward alkyl hydroperoxides and peroxynitrite, and PRDX6 reduces both H 2 O 2 and LOOHs

Higher dose antioxidant protocols are often chosen for individuals seeking more intensive support related to oxidative stress or recovery

Based on the important role of ferroptosis in AD pathogenesis, inhibiting ferroptosis has become a significant strategy to reduce neuronal damage in AD in preclinical studies

Furthermore, PMNs expressing Syk proteins with non-functional Src Homology 2 (SH2) domains fail to induce ROS production in response to integrin stimulation (Mocsai et al., 2006)