glutathione iron and parkinson& 39 Targeting Ferroptosis in Parkinson's Disease: Mechanisms Emerging Therapeutic Strategies Parkinson's disease: Alterations in iron
Description
Thioredoxin reductases In mammals, three selenocysteine-containing thioredoxin reductase (TXNRD) isoenzymes have been identified in the thioredoxin system: cytosolic TXNRD1, mitochondrial TXNRD3, and testes-specific thioredoxin glutathione reductase (TXNRD3, also known as TGR)
Small 17 , e2006484 (2021)
This nuclear localization in elderly Leydig cells correlated with reduced expression of 3-HSD, a crucial enzyme for testosterone synthesis, suggesting a link between nuclear FOXO4 and age-related decline in testosterone production [2]
It protects the cancerous cells by conferring resistance to chemotherapeutic drugs
