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doi: 10.1177/088307380001501203 26

Form / Delivery Method: Sublingual troche or nasal spray (based on pharmacy fulfillment)

The interesting points regarding the clinical manifestations and the course of our patient were the fact that granulomatous cheilitis preceded the diagnosis of CD by two years, the fact that the enlargement of the lower lip occurred in parallel with the clinical exacerbations of CD and that the administration of corticosteroids resulted not only in improvement of bowel symptoms but also in diminishment of the size of the lip swelling

It is obvious that sometimes, HAs and paraproteins are actually the same clone of immunoglobulins, but paraproteins can be present in all clinical specimens and tissues, whereas HAs are usually absent in urine [1161,1166]