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In particular, USP22 raised GSH content and reduced the occurrence of ferroptosis in cardiomyocytes by activating the Sirt1-p53/SLC7A11 axis [252]
In the intensely competitive GLP-1 drug market, simply enhancing drug efficacy is no longer sufficient to make new products stand out
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Finally, amelioration of the G/F-actin ratio restores the disruption of the YAP signal induced by high glucose and upregulates the transcription factors Neurod1, Foxa1, and Foxa2, which are responsible for controlling L-cell differentiation [30] (Fig
