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For example: A review on mesotherapy for melasma found that intradermal therapies (e.g., with tranexamic acid and ascorbic acid) can produce significant reductions in visceral pigment index scores

GHS-R is a G-protein coupled receptor that has great druggable potential
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Baumgardner JN, Shankar K, Hennings L, Albano E, Badger TM, Ronis MJ (2008) N-acetylcysteine attenuates progression of liver pathology in a rat model of nonalcoholic steatohepatitis