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what has glutathione Glutathione: Master Antioxidant, Reducing Oxidative Stress, and Detoxification What is glutathione? - Aktif
Description
Although the amount is small and usually harmless, some people prefer to avoid it, especially smokers or those with impaired detox function

Krijt J, Vackova M, Kozich V (2001)

Lower Zinc Levels: There is some evidence that long-term, high-dose glutathione use can affect the bodys zinc levels

In my practice, I do occasionally recommend glutathione and polypodium supplements for melasma (more so for skin lightening)
