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After 1 month of treatment in pernicious anemia patients, the once weekly dosing of 500 mcg B12 intranasal gel resulted in a statistically significant increase in B12 levels when compared to a once monthly 100 mcg IM dose

It's worth noting that these injections have been successfully used in combination with weight loss programs for over 30 years

A study published in the Journal of Clinical and Experimental Medicine found that high-dose IV vitamin C reduced symptoms and shortened the duration of mono in infected individuals (Padayatty et al, 2003)