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Concurrently, sUA mediates the degradation pathway of the IRS2 protein and activates Adenosine 5-monophosphate (AMP)-activated protein kinase (AMPK)/mammalian target of rapamycin (mTOR) in macrophages, thereby reducing energy consumption which leads to IR (60)
Fine lines around the eyes and mouth soften because the underlying matrix is more hydrated and structurally supported
NeuroRehabilitation, 45:273-283
Fernandes, R
