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however, the translation of these results into the clinical setting is essential because past attempts to develop such formulations by other groups have been unable to induce IGF-1 in man

5 T lymphocytes activation by intravenous injection of Con A in mice leads to infiltration of CD4+ T lymphocytes in the liver tissue, and infiltrated CD4+ T lymphocytes secrete a large amount of cytokines such as tumor necrosis factor- (TNF- ), interferon- (IFN- ) and interleukin (IL)-2

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