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Immune therapy-PI combination might enhance PI sensitivity, as evidenced in multiple myeloma (MM), where IL-33 enhances Bortezomib sensitivity by inducing excessive ROS
PMID: 42170236 Mater Today Bio 2025 Oct 2:35:102364
Glucose withdrawal activates multiple TKs and selected intracellular signaling pathways Having established that PTEN influences but does not fully control the sensitivity to glucose withdrawal, we sought to gain a more detailed perspective on which TKs were activated by glucose withdrawal
Remember, if it is given IV this is because the liver is in big trouble
