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We found that RP/MRD cells were more sensitive to an oxidative phosphorylation inhibition (IACS-010759), and to an SWI/SNF inhibitor (AU-15330), than the starting lines, and were also extremely sensitive to cotreatment with a bi-steric mTORC1 inhibitor

S15, all formulations had no obvious cytotoxicity to 3T3 cells within the given concentration range

doi: 10.1002/jat.3303 73 PizzinoG.IrreraN.CucinottaM.PallioG.ManninoF.ArcoraciV.et al

Digiacomo et al
