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Age-associated loss of Sirt1-mediated enhancement of glucose-stimulated insulin secretion in beta cell-specific Sirt1-overexpressing (BESTO) mice

PMID: 41255515 Proc Natl Acad Sci U S A Mitochondrial ROS triggers mitophagy through activating the DNA damage response signaling pathway

The progression of colitis was monitored using the Disease Activity Index (DAI) scoring system (Yao et al., 2020), which assesses the severity of colitis based on specific parameters

The calvariectomy procedure included, medially to the superior temporal lines and temporalis muscle attachments, 6 burr holes drilled in three horizontal lines (just basal from the posterior interocular line (two rostral burr holes), just rostral to the lambdoid suture (and transverse sinuses) on both sides (two basal burr holes) and in line between the basal and rostral burr holes (two middle burr holes))