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Un dispositif transdermique, communment appel par son nom anglais patch, se prsente comme un timbre adhsif contenant une substance mdicamenteuse et destin tre coll sur la peau

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After reaching 65/70 years of age, the circadian rhythm of melatonin secretion almost completely disappears. MELATONIN IN SLEEP DISORDERS Melatonin as a hormone regulating the day-night circadian rhythm and seasonal biorhythm also participates in the process of mood, sleep, and its quality