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Pregnancy : Many women get dark patches on their face during pregnancy
doi:10.1016/j.schres.2007.06.023
Unfortunately for AOD 9604, it did not pass this study
When cell membranes are exposed to various stimuli, vast amounts of AA are released from PLs by phospholipase A2 (PLA2) and phospholipase C (PLC) [54,55,56], which is then metabolized into biologically active inflammatory mediators like eicosanoids prostaglandin (PG), interleukin (IL), tumor necrosis factor (TNF), and leukotriene (LT)
