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Description
Studies in rodents have shown that feeding animals a high-fat diet lower ObRa levels within the hypothalamus 24,35 and, consistent with this, leptin transport is decreased in obese humans
Once mixed with liquid, refrigerate and use within 30 days, avoiding repeated freezing and thawing
Spine Journal Meeting Abstracts, 2003:28
The water itself doesn't "go bad" in a dramatic way, but you can no longer rely on the manufacturer-validated preservative activity
