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Dosing & Reconstitution Guide A single practical dilution with accurate once-daily dosing, step by step Standard / Gradual Approach (3 mL = ~1.67 mg/mL) Reconstitute: Add 3.0 mL bacteriostatic water to one 5 mg vial final concentration ~1.67 mg/mL (1,667 mcg/mL)

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All mice were fed a nutritionally adequate liquid control diet for a week, and then divided into six groups (control, model, PGPIPN I, PGPIPN II, PGPIPN III and GSH) with 10 mice in each group