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It has been reported that sorafenib can induce ferroptosis in tumor cells through the p62-kelch-like ECH-associated protein 1-NRF2 pathway to achieve anti-tumor efficacy (33)
[DOI] [PMC free article] [PubMed] [Google Scholar] 197.Thery T., Lynch K.M., Zannini E., Arendt E.K
Like what we observed for the unaffected children, we found that overall GPx3 levels between stage 2 and stage 3 are not significantly different ( p = 0.79) (Supplementary Figs
B12
