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Many people start strong, but fatigue, cravings, low motivation, and frustration can make it difficult to stay on track

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Oxidative Stress and Cellular Stability Oxidative stress occurs when reactive oxygen species exceed cellular defenses, damaging proteins, lipids, and DNA

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Repetitive wrist movements (e.g., tennis, golf, painting, typing, carpentry) 2

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Thus, timing-dependent (t-) LTP occurs when a presynaptic spike is followed by a postsynaptic spike, whereas t-LTD is induced when this order is reversed (Markram et al., 1997

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