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paragallinarum is profound, affecting not only its survival under oxidative stress but also its ability to colonize and cause disease in the host

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These conditions result in low IGF-I concentrations, and changes in IGF-I positively correlate with changes in lean body mass[369, 370], as well as reversal of acute catabolic states is associated with an increase in IGF-I levels[371, 372]

Inhibition of Notch uncouples Akt activation from hepatic lipid accumulation by decreasing mTorc1 stability
