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As expected, adverse events were frequent and typical of opioid-related side effects

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LINK Loukas M, Colborn GL, Tubbs RS: John Elias Skandalakis, MD, PhD, FACS (1920-2009)

This study compared 60 mg IV edaravone for 6 cycles (24 weeks) with placebo in 137 patients with ALS and successfully met the primary endpoint of adjusted mean difference of ALSFRS-R [140]
