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doi: 10.1038/jid.2014.297
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Though there is limited information to support transdermal application of medication for ED, some data exists to suggest efficacy
Upon recruitment, the membrane adhesion proteins such as intercellular adhesion molecule-1 on endothelial cells are up-regulated, and the proteins including integrin 2, macrophage-1 antigen, and lymphocyte function-associated antigen 1 are overexpressed on the neutrophil membrane, together facilitating the transmigration
