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Description
Several NRF2 activators are currently undergoing clinical trials, including dimethyl fumarate, sulforaphane, bardoxolonemethyl, and omaveloxolone, whereas the pharmacokinetics issues and offtarget effects remain challenges [171, 172, 173, 174]

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doi: 10.1155/2021/2962792

Biotechnol 44:14652 [DOI] [PMC free article] [PubMed] [Google Scholar] 106.Sullivan MR, Mattaini KR, Dennstedt EA, Nguyen AA, Sivanand S, et al