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As shown in Scheme 81, 12( R )-LOX forms the 9( R )-hydroperoxide on linoleate esters, which is isomerized by eLOX3, and the NAD-dependent dehydrogenase SDR9C7 oxidizes the 13-hydroxy group to the ketone

HepaRG cell line is the second most used cellular model and is generally considered as a good surrogate for PHHs when investigating liver metabolism and detoxification (Rodrigues et al., 2018

This result was different from reports that hyperreflective foci in OCT were the most important predictor of neovascular conversion in drusen accompanied cases 26

Ligands measuring presynaptic processes may be more sensitive in PD due to relative preservation, or even upregulation of postsynaptic dopamine receptors early in the disease