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J Clin Lipidol 2016;10:1248-58

melanogaster Strains Lamellocytes produce PPO3, a key enzyme responsible for the melanization of the capsule formed around the parasitoids infecting D

Alterations in the normal activities of SM-cycle enzymes have been linked to many central nervous system-related pathologies such as Alzheimers, Parkinsons, ischemia/hypoxia, depression, schizophrenia or Niemann-Pick diseases 19 .Specific SL functions have often been characterized in cells with decreased amounts of SL, using either SL-degrading enzymes (e.g