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Oxidative stress is the leading factor that produces damage in cell structures, i.e., in membranes, proteins, lipids and DNA

After intratracheal administration or nebulization, ciprofloxacin, doxorubicin, and vancomycinloaded microrobots effectively inhibit acute Pseudomonas aeruginosa pneumonia, lung metastasis, and acute methicillinresistant Staphylococcus aureus pneumonia, respectively

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Notably, treatments with ferroptosis inhibitor (ferrostatin-1), necroptosis inhibitor (necrostatin-1), and an oxidative stress (N-acetyl cysteine) all were unsuccessful in terminating copper ionophore-induced cell death [22]