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Further confirmation of this outcome was obtained through fluorescence microscopy, revealing a reduction in the fluorescence intensity of ROS after HT pretreatment (Fig

In the stage of cancer progression, administration of high doses of vitamin C, especially in combination with redox-active metals (copper, iron) may increase the cellular prooxidant state triggering cytotoxicity of cancer cells (Pawlowska et al

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Frequent intake of eggs, meat, and legumes was linked to higher selenium concentrations, while margarine and fish consumption inversely affected selenium levels, although their overall dietary influence was modest