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Headache is reported by some patients and may be related to dehydration from gastrointestinal side effects or direct pharmacological effects

CrossRef Interleukin-10 Polymorphisms in Association with Prognosis in Patients with B-Cell Lymphoma Treated by R-CHOP Min Kyeong Kim, Kyong-Ah Yoon, Eun Young Park, Jungnam Joo, Eun Young Lee, Hyeon-Seok Eom, Sun-Young Kong Genomics & Informatics.2016

Although some groups performed experiments on small samples [144, 145], these are not statistically solid because numerical samples of about 50 patients are not sufficient for these methods