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*Distributions in excess of the Funds current and accumulated earnings and profits are treated as a tax-free return of capital to the extent of your basis in Shares and as capital gain thereafter

Endogenous Opioid System The endogenous opioid system is a highly diverse peptide neurotransmitter system comprising opioid receptors and three major neuropeptide families containing multiple member peptides

Assessment of Cell Viability ARPE-19 cell viability was evaluated by performing the 3-(4,5-dimethylthiazol-2-yl)5-(3-carboxymethoxyphenyl)2-(4-sulfophenyl)2 H-tetrazolium (MTS) assay as previously described [25]