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Studies revealed that this drug improved behavioral, biochemical and histopathological parameters in a streptozotocin-induced rat model of AD (Fanoudi, et al

Higher magnification images suggested a reduction in MBP and MOG expression in the corpus callosum 24 h post CPZ-treatment (Figures 2B,E)

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Over the course of the 5-weeks, cpz dosing resulted in 6NTac mice have a significant decrease BW compared to 6J mice over varying days (g and % change) (Figure 1 B and C)
