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Ger Med Sci
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HGH and IGF-1 are known to play crucial roles in stimulating osteoblast activity (the cells that build new bone)

Hence, mTORC1 sense glutamine availability in both directions: when glutamine is available, mTORC1 is activated via -ketoglutarate production

doi: 10.1007/s00204-005-0037-1
