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Whether DNA methylation is increased by high levels of methionine is still unclear, since, for example, excess methionine may impair DNA methylation by inhibiting remethylation of homocysteine ( Reference Dunlevy, Burren and Chitty 92 )
Oxysterols also affect serotonin synthesis and neuron viability (Dodge et al., 2021)
Site-directed mutagenesis for amino acid substitution was performed using a QuikChange kit (Stratagene)
