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Interestingly, ERK1/2 signaling plays an important role in memory formation and retrieval [125], and brains exposed to the A peptide have decreased activation of ERK1/2 due, in part, to a deficiency in protein kinase C II (PKC II)-mediated signaling [124]
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Clinical Presentation of GH Deficiency GH deficiency can present either in isolation (isolated GHD - IGHD) or in combination with other pituitary hormone insufficiencies (multiple pituitary hormone deficiency - MPHD)
