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Human studies suggest that under conditions of extreme metabolic stress, such as glycogen depletion, myelin lipids may be mobilized as a local energy reserve, resulting in a transient reduction of myelin contenta phenomenon referred to as metabolic myelin plasticity

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Furthermore, we highlight limitations of the current research on utility of AOXs for treatment of infertile couples and the need for well-designed studies that can bridge the gap between research and practice in this regard