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Inflammasomes, particularly the NLRP3 inflammasome, play a central role in regulating this phase by sensing both pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs) released during injury, such as those generated in thermal burns
TrxR and GR are NADPH-dependent flavoenzymes that transfer electrons to oxidized Trx and GSSG, respectively
179 Curcumin may also reduce serum cholesterol by increasing the production of the LDL receptor, 180,181 but despite successes in animal models, human data on the anti-hypercholesterolemic effects of curcumin is conflicting
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