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Growth Hormone Receptor Gene is Essential for Chicken Mitochondrial Function In Vivo and In Vitro

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After thresholding for statistically significant gene hits across control and NPC1 -knockout cells, we identified 389 genes that, when knocked down, sensitize cells to LLOMe (sensitizing hits, indicating a damage-protective gene function) and 322 desensitizing gene hits

Pairwise correlation between all biomarkers also showed that the CognitionBrain age gap was largely independent from other biomarkers (Extended Data Fig
