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Correspondingly, standard distance-dependent dielectric constant at 2.0 , which specifies the small backbone fluctuations and electronic polarization in the protein, and conjugated gradient algorithm were used in the successive enhancement of protein crystal structure, including merging of hydrogen atoms, at root mean square deviation (RMSD) of 0.30 under optimized potentials for liquid simulations-3e force field (OPLS-3e) using Protein preparation wizard in the Schrdinger suite-2020.4 45

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There is no clear relationship between the oral bacterial community and lung function in healthy organisms, but changes in the oral microbiota may affect lung disease because the lungs are exposed to the oral microbial community through respiratory movements such as breathing and coughing