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This Review examines sex in IBD pathophysiology and clinical manifestation and provides a frame for improving clinical and preclinical IBD studies by considering sex an essential factor.

Aging-associated cellular senescence and stem cell exhaustion inhibit adipocyte renewal, leading to excessive hypertrophy and low-grade inflammation

Researchers have implicated mercury (Hg) exposure in the pathogenesis of autism spectrum disorder (ASD) through multiple mechanisms, including oxidative stress, mitochondrial dysfunction, and glutamatergic dysregulation

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