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In June 2019, the FDA approved PT-141 as an on-demand treatment for this condition, marking a significant milestone in womens health

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Glucagon-like peptide-1 (GLP-1) receptor agonists, such as semaglutide, achieve significant weight loss primarily through central appetite suppression [9, 10]

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Its structural design specifically optimises melanocortin-1 and melanocortin-4 receptor activation whilst minimising activity at other melanocortin receptor subtypes

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