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Description
Safe storage within the temperature of -20C to 4C (4F to 39F) is recommended
Various nanomaterials have been shown to improve drug delivery to the brain [21, 22], and several BBB-compliant strategies have been developed based on its physiology
Kynurenine, a metabolite of tryptophan, upregulates T-cell PD-1 levels by inducing and activating the aryl hydrocarbon receptor (AhR), while AhR upregulates transporters to promote T cells to uptake kynurenine, forming a positive feedback loop and inhibiting anti-tumor immune responses (Liu et al., 2018)
Gaskill BN, Garner JP
