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Early research suggests that MOTS-C peptide may influence pathways such as AMPK activation and antioxidant gene expression, hinting at potential roles in metabolic health, physical performance, and age-related decline

To focus on oxidative stress as a main damaging factor in an in vitro model is reasonable, as the diverse upstream causes for PN (hyperglycemia, dyslipidemia, some chemotherapeutics, alcohol abuse) converge into one prominent metabolic disturbance: the production of ROS and, thus, increased oxidative stress

doi:10.1097/JU.0000000000001982

study, effects in fast-aging mice were observable within 10-14 days of treatment initiation