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Conversely, granulosa cells show reduced GPx4 expression and ferritinophagy-mediated iron overload, leading to heightened susceptibility to ferroptosis and impaired oocyte quality ( Therapeutic approaches targeting these pathways have been explored

Recent studies have been shown that ZO-1 deficient cells are still able to form normal TJ structures and show normal permeability

Proximal cysteines that enhance lysine n-acetylation of cytosolic proteins in mice are less conserved in longer-living species

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