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These changes in Cyclin D1 expression were associated with decreased serum ALT/AST and improved liver regeneration in wild type and TPH1-/- plus 5-HTP mice receiving APAP, suggesting that 5-HT likely facilitates activation of Cyclin D1-mediated regeneration pathways

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Royal Society of Chemistry, Cambridge, pp 38 Samara K, Liu C, Soldevila-Pico C et al (2006) Betaine resolves severe alcohol-induced hepatitis and steatosis following liver transplantation

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