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Deubiquitinase USP20 is phosphorylated upon AR stimulation, in conditions such as cardiac pressure overload, regulating 1 -AR and 2 -AR trafficking in cultured cells, and in mouse hearts
Acknowledgments The authors are grateful to Brazilian agencies FAPERJ, INCT-Entomologia Molecular, CNPq and CAPES for supporting this project
The microbiome, especially the fibers it ferments into short-chain fatty acids, appears to help keep the barrier stable, though much of the detailed evidence is from laboratory and animal studies
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