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During the adolescence, the topdown control of prefrontal cortex over the VTA-NAc circuit is relatively weak, resulting in a chronically VTA-induced activation of NAc (Crews et al., 2007)
doi: 10.1371/journal.pone.0099219 202 SainiAKPatelRJSharmaSSH SAK
Pyroptosis is a novel form of programmed cell death, which was identified after apoptosis and necrosis
