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10.1371/journal.pone.0063773 Summary Keywords psychiatry, mood disorder, neuropsychaitric disorders, behavior, biological rhythms, chronobiology, 6-sulfatoxymelatonin (aMT6s), biomarker Citation Tonon AC, Pilz LK, Markus RP, Hidalgo MP and Elisabetsky E (2021) Melatonin and Depression: A Translational Perspective From Animal Models to Clinical Studies

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Cell Line: 22Rv1 cells Concentration: 0.1 M, 0.5 M, 1 M, 10 M Incubation Time: 6 hours Result: Significant reduction of downstream phosphorylation of RNA Pol II at Ser2 and Ser7, and diminished phosphorylation at Ser5
