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Greger (typically 5 minutes, with transcripts & references) Also: The 411 on Vitamin B12 Dec 2023 The Symptoms of Vitamin B12 Deficiency and Optimal Dosage for Adults - Dr

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Later studies confirmed even larger increases (up to 100%) when arterialized blood (rather than venous blood) was sampled (246, 247)
Protocol: Starting dose: 0.6mg daily for week 1 Escalation: Increase by 0.6mg weekly until reaching 3mg daily Timing: Same time daily, ideally before meals Cost: $1,300-1,500/month without insurance The established safety record spanning over 10 years provides reassurance for patients concerned about newer medications' long-term risks
