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Description
This indicates that the oxidation of PUFA by LOXs through a PHKG2-dependent iron pool is required for ferroptosis, and that the covalent inhibition of the catalytic selenocysteine in GPX4 prevents the elimination of PUFA hydroperoxides

Peripheral SMN restoration is essential for long-term rescue of a severe spinal muscular atrophy mouse model
Ferric ions have been shown to bind to a conserved His50 residue in molar equivalents which provides the coordination site for the metal ion

Conditions like celiac or Crohn's disease can impair B12 absorption
