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Steatosis may be caused by the interaction of diet, genetic factors, gut microbiota, and lipogenesis through upregulation of lipogenic transcription factors, such as SREBP1c, etc

Cellular Function: Glutathione is required for the manufacture of many cellular proteins, is involved in the synthesis and repair of DNA, and is a cofactor for many cellular enzymes involved in overall cell function

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Highlights: RT-AM is cell permeable and can generate RT upon intracellular esterase cleaveage Easily quantitate GSH levels in live cells using confocal microscopy/FACS Signals from blue and green channels allow for deduction of GSH concentration, given appropriate calibration curve For calibration curve, see: RealThiol (RT) Glutathione (GSH) Calibration Probe Subcellular detection and localization of GSH is important in understanding the modulation of redox status, the effect of drugs, and the mechanisms of detoxification